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Dr. Beatrice Adelizzi “Tuning non-covalent interactions: from synthetic supramolecular copolymers to proteins and DNA”
January 17 @ 3:30 pm
Project Leader – Inkjet Synthesis at DNA Script
Despite being inherently weak and dynamic, non-covalent interactions play a fundamental role in dictating the organization of molecules, materials, and (bio)polymers. Understanding such interactions allows one to tune their strength, predict the self-organization of the system, and enhance (or inhibit) targeted reactivities. Despite the wealth of research in the field of supramolecular chemistry, the challenge of mastering a system becomes exponentially more difficult as its complexity is increased. This lecture will walk through the understanding of non-covalent interactions in three increasingly complex systems: supramolecular copolymers for use in optoelectronic devices, dynamic equilibria between proteins and tailored ligands for use in selective bioimaging, and multiplex enzymatic synthesis of DNA using inkjet technology for applications in gene assembly and protein engineering.