2008 |
Palma, Carlos-Andres ; Bonini, Massimo ; Llanes-Pallas, Anna ; Breiner, Thomas ; Prato, Maurizio ; Bonifazi, Davide ; Samori, Paolo Pre-programmed bicomponent porous networks at the solid-liquid interface: the low concentration regime Journal Article In: CHEMICAL COMMUNICATIONS, (42), pp. 5289–5291, 2008, ISSN: 1359-7345. @article{palma_pre-programmed_2008, title = {Pre-programmed bicomponent porous networks at the solid-liquid interface: the low concentration regime}, author = {Palma, Carlos-Andres and Bonini, Massimo and Llanes-Pallas, Anna and Breiner, Thomas and Prato, Maurizio and Bonifazi, Davide and Samori, Paolo}, doi = {10.1039/b811534f}, issn = {1359-7345}, year = {2008}, date = {2008-01-01}, journal = {CHEMICAL COMMUNICATIONS}, number = {42}, pages = {5289--5291}, abstract = {The control over the formation of a bicomponent porous network was attained by self-assembly at the solid-liquid interface, exploiting triple H-bonds between melamine and bis-uracyl modules.}, keywords = {}, pubstate = {published}, tppubtype = {article} } The control over the formation of a bicomponent porous network was attained by self-assembly at the solid-liquid interface, exploiting triple H-bonds between melamine and bis-uracyl modules. |
Palma, Matteo ; Levin, Jeremy ; Debever, Olivier ; Geerts, Yves ; Lehmann, Matthias ; Samori, Paolo Self-assembly of hydrogen-bond assisted supramolecular azatriphenylene architectures Journal Article In: SOFT MATTER, 4 (2), pp. 303–310, 2008, ISSN: 1744-683X. @article{palma_self-assembly_2008, title = {Self-assembly of hydrogen-bond assisted supramolecular azatriphenylene architectures}, author = {Palma, Matteo and Levin, Jeremy and Debever, Olivier and Geerts, Yves and Lehmann, Matthias and Samori, Paolo}, doi = {10.1039/b713570j}, issn = {1744-683X}, year = {2008}, date = {2008-01-01}, journal = {SOFT MATTER}, volume = {4}, number = {2}, pages = {303--310}, abstract = {We report on the self-assembly of a functionalized hexaazatriphenylene into supramolecular architectures where the single hexaazatriphenylene molecules are held together primarily through intermolecular hydrogen bonds between amide units. Wide and small angle X-ray scattering, polarized light microscopy, and differential scanning calorimetry revealed bulk self-organization into columnar structures. At the surfaces, scanning force microscopy experiments showed that it is possible to drive the self-organization from solutions of N-(2-ethylhexyl)-hexacarboxamidohexaazatriphenylene, towards either layers on a conductive surface like graphite or supramolecular anisotropic assemblies on an electrically insulating substrate such as muscovite mica. The growth of this latter type of architecture is primarily driven by the physical dewetting of the solution cast on the surface combined with intermolecular hydrogen bonds between the amide moieties exposed in the peripheral positions that lead to the formation of the columnar stack. Therefore, the anisotropic supramolecular azatriphenylene assemblies observed in the bulk have been also observed in thin films on a substrate poorly interacting with the adsorbate. In view of the interesting electronic properties of hexaazatriphenylene based architectures as n-type semiconductors, these results might be of interest for applications in the field of organic electronics.}, keywords = {}, pubstate = {published}, tppubtype = {article} } We report on the self-assembly of a functionalized hexaazatriphenylene into supramolecular architectures where the single hexaazatriphenylene molecules are held together primarily through intermolecular hydrogen bonds between amide units. Wide and small angle X-ray scattering, polarized light microscopy, and differential scanning calorimetry revealed bulk self-organization into columnar structures. At the surfaces, scanning force microscopy experiments showed that it is possible to drive the self-organization from solutions of N-(2-ethylhexyl)-hexacarboxamidohexaazatriphenylene, towards either layers on a conductive surface like graphite or supramolecular anisotropic assemblies on an electrically insulating substrate such as muscovite mica. The growth of this latter type of architecture is primarily driven by the physical dewetting of the solution cast on the surface combined with intermolecular hydrogen bonds between the amide moieties exposed in the peripheral positions that lead to the formation of the columnar stack. Therefore, the anisotropic supramolecular azatriphenylene assemblies observed in the bulk have been also observed in thin films on a substrate poorly interacting with the adsorbate. In view of the interesting electronic properties of hexaazatriphenylene based architectures as n-type semiconductors, these results might be of interest for applications in the field of organic electronics. |
De Luca, Giovanna ; Liscio, Andrea ; Nolde, Fabian ; Scolaro, Luigi Monsu ; Palermo, Vincenzo ; Muellen, Klaus ; Samori, Paolo Self-assembly of discotic molecules into mesoscopic crystals by solvent-vapour annealing Journal Article In: SOFT MATTER, 4 (10), pp. 2064–2070, 2008, ISSN: 1744-683X. @article{de_luca_self-assembly_2008, title = {Self-assembly of discotic molecules into mesoscopic crystals by solvent-vapour annealing}, author = {De Luca, Giovanna and Liscio, Andrea and Nolde, Fabian and Scolaro, Luigi Monsu and Palermo, Vincenzo and Muellen, Klaus and Samori, Paolo}, doi = {10.1039/b807391k}, issn = {1744-683X}, year = {2008}, date = {2008-01-01}, journal = {SOFT MATTER}, volume = {4}, number = {10}, pages = {2064--2070}, abstract = {Solvent vapour annealing (SVA) is used to control the reorganization of ultrathin films of three different polycyclic aromatic hydrocarbons self-assembled on solid surfaces. To this end, two perylene-bis( dicarboximide) (PDI) derivatives exposing branched side alkyl chains with different length and a dodecyl substituted hexa-peri-hexabenzocoronene (HBC) have been used, in view of their n- and p-type semiconducting nature. For all the three molecules, nanoscopic crystals grown from solution by spin-coating and drop-casting undergo reorganization into sub-millimetric fibers, domes and needles, proving the general applicability of the SVA method. Moreover, such an approach exhibits a mass transport of the molecules on surfaces over hundreds of microns. The self-healing of the films through SVA treatment leads to a decrease of the structural defects and an increase in the lateral size of the self-assembled domains, ultimately providing an improved 3D conjugation. Therefore the SVA can be considered an important strategy with potential to enhance the performance of macroscopic organic electronic devices.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Solvent vapour annealing (SVA) is used to control the reorganization of ultrathin films of three different polycyclic aromatic hydrocarbons self-assembled on solid surfaces. To this end, two perylene-bis( dicarboximide) (PDI) derivatives exposing branched side alkyl chains with different length and a dodecyl substituted hexa-peri-hexabenzocoronene (HBC) have been used, in view of their n- and p-type semiconducting nature. For all the three molecules, nanoscopic crystals grown from solution by spin-coating and drop-casting undergo reorganization into sub-millimetric fibers, domes and needles, proving the general applicability of the SVA method. Moreover, such an approach exhibits a mass transport of the molecules on surfaces over hundreds of microns. The self-healing of the films through SVA treatment leads to a decrease of the structural defects and an increase in the lateral size of the self-assembled domains, ultimately providing an improved 3D conjugation. Therefore the SVA can be considered an important strategy with potential to enhance the performance of macroscopic organic electronic devices. |
Mativetsky, Jeffrey A; Palma, Matteo ; Samori, Paolo Exploring electronic transport in molecular junctions by conducting atomic force microscopy Incollection In: {Samori, P} (Ed.): STM AND AFM STUDIES ON (BIO)MOLECULAR SYSTEMS: UNRAVELLING THE NANOWORLD, 285 , pp. 157–202, 2008, ISBN: 978-3-540-78394-7. @incollection{mativetsky_exploring_2008, title = {Exploring electronic transport in molecular junctions by conducting atomic force microscopy}, author = {Mativetsky, Jeffrey A. and Palma, Matteo and Samori, Paolo}, editor = {{Samori, P}}, doi = {10.1007/128_2007_25}, isbn = {978-3-540-78394-7}, year = {2008}, date = {2008-01-01}, booktitle = {STM AND AFM STUDIES ON (BIO)MOLECULAR SYSTEMS: UNRAVELLING THE NANOWORLD}, volume = {285}, pages = {157--202}, series = {Topics in Current Chemistry-Series}, abstract = {Measuring the electronic transport properties of single molecules and molecular nanostructures is an interesting and challenging new frontier from both a fundamental as well as technological perspective. Conducting atomic force microscopy (C-AFM) represents an attractive line of approach given its ability to position a sharp electrical probe with nanometer-scale precision and a controlled nano-Newton-range force. Moreover, the combination of AFM imaging and C-AFM electrical characterization enables investigation of the relationship between structure and function in molecular architectures. The aim of the present review is twofold: (1) to introduce the C-AFM method, alongside a discussion of experimental practices, capabilities and limitations, and (2) to provide an overview of the application of C-AFM to different types of molecular systems. These include alkane-based and oligomer-based self-assembled monolayers, molecular crystals, conducting polymer films, molecular wires (e.g. carbon nanotubes), and electrically active biomolecules. We will also discuss C-AFM approaches that allow single molecule measurements as well as other recent developments.}, keywords = {}, pubstate = {published}, tppubtype = {incollection} } Measuring the electronic transport properties of single molecules and molecular nanostructures is an interesting and challenging new frontier from both a fundamental as well as technological perspective. Conducting atomic force microscopy (C-AFM) represents an attractive line of approach given its ability to position a sharp electrical probe with nanometer-scale precision and a controlled nano-Newton-range force. Moreover, the combination of AFM imaging and C-AFM electrical characterization enables investigation of the relationship between structure and function in molecular architectures. The aim of the present review is twofold: (1) to introduce the C-AFM method, alongside a discussion of experimental practices, capabilities and limitations, and (2) to provide an overview of the application of C-AFM to different types of molecular systems. These include alkane-based and oligomer-based self-assembled monolayers, molecular crystals, conducting polymer films, molecular wires (e.g. carbon nanotubes), and electrically active biomolecules. We will also discuss C-AFM approaches that allow single molecule measurements as well as other recent developments. |
Giuseppone, Nicolas ; Schmitt, Jean-Louis ; Allouche, Lionel ; Lehn, Jean-Marie DOSY NMR experiments as a tool for the analysis of constitutional and motional dynamic processes: Implementation for the driven evolution of dynamic combinatorial libraries of helical strands Journal Article In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47 (12), pp. 2235–2239, 2008, ISSN: 1433-7851. @article{giuseppone_dosy_2008, title = {DOSY NMR experiments as a tool for the analysis of constitutional and motional dynamic processes: Implementation for the driven evolution of dynamic combinatorial libraries of helical strands}, author = {Giuseppone, Nicolas and Schmitt, Jean-Louis and Allouche, Lionel and Lehn, Jean-Marie}, doi = {10.1002/anie.200703168}, issn = {1433-7851}, year = {2008}, date = {2008-01-01}, journal = {ANGEWANDTE CHEMIE-INTERNATIONAL EDITION}, volume = {47}, number = {12}, pages = {2235--2239}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Ruff, Yves ; Lehn, Jean-Marie Glycodynamers: Fluorescent dynamic analogues of polysaccharides Journal Article In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47 (19), pp. 3556–3559, 2008, ISSN: 1433-7851. @article{ruff_glycodynamers:_2008-1, title = {Glycodynamers: Fluorescent dynamic analogues of polysaccharides}, author = {Ruff, Yves and Lehn, Jean-Marie}, doi = {10.1002/anie.200703490}, issn = {1433-7851}, year = {2008}, date = {2008-01-01}, journal = {ANGEWANDTE CHEMIE-INTERNATIONAL EDITION}, volume = {47}, number = {19}, pages = {3556--3559}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Lehn, Jean-Marie A Jubilee 60th Congress of the Association of Czech and Slovak chemical company. Olomouc, 1st-4th September 2008 - Abstracts Journal Article In: CHEMICKE LISTY, 102 (8), pp. 595–759, 2008, ISSN: 0009-2770. @article{lehn_jubilee_2008, title = {A Jubilee 60th Congress of the Association of Czech and Slovak chemical company. Olomouc, 1st-4th September 2008 - Abstracts}, author = {Lehn, Jean-Marie}, issn = {0009-2770}, year = {2008}, date = {2008-01-01}, journal = {CHEMICKE LISTY}, volume = {102}, number = {8}, pages = {595--759}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Sreenivasachary, Nampally ; Lehn, Jean-Marie Structural selection in G-quartet-based hydrogels and controlled release of bioactive molecules Journal Article In: CHEMISTRY-AN ASIAN JOURNAL, 3 (1), pp. 134–139, 2008, ISSN: 1861-4728. @article{sreenivasachary_structural_2008, title = {Structural selection in G-quartet-based hydrogels and controlled release of bioactive molecules}, author = {Sreenivasachary, Nampally and Lehn, Jean-Marie}, doi = {10.1002/asia.200700041}, issn = {1861-4728}, year = {2008}, date = {2008-01-01}, journal = {CHEMISTRY-AN ASIAN JOURNAL}, volume = {3}, number = {1}, pages = {134--139}, abstract = {A guanosine-5'-hydrazide can entrap biologically interesting molecules such as acyclovir, vitamin C, and vancomycin into its hydrogel network. Controlled release of these molecules was monitored by H-1 NMR spectroscopy. The hydrazide may potentially form mixed G-G quartets with analogous compounds containing a guanine Group. H-1 NMR spectroscopy was used to study the inclusion of various guanine derivatives into the hydrogel. The structural selectivity was found to depend strongly on both the shape and the charge of the additive and may arise from the strong cohesion of the supramolecular architecture of the gel and the resulting resistance to perturbation by foreign bodies. Hydrogels thus offer a promising medium for highly selective, controlled release of bioactive substances.}, keywords = {}, pubstate = {published}, tppubtype = {article} } A guanosine-5'-hydrazide can entrap biologically interesting molecules such as acyclovir, vitamin C, and vancomycin into its hydrogel network. Controlled release of these molecules was monitored by H-1 NMR spectroscopy. The hydrazide may potentially form mixed G-G quartets with analogous compounds containing a guanine Group. H-1 NMR spectroscopy was used to study the inclusion of various guanine derivatives into the hydrogel. The structural selectivity was found to depend strongly on both the shape and the charge of the additive and may arise from the strong cohesion of the supramolecular architecture of the gel and the resulting resistance to perturbation by foreign bodies. Hydrogels thus offer a promising medium for highly selective, controlled release of bioactive substances. |
Chow, Cheuk-Fai ; Fujii, Shunsuke ; Lehn, Jean-Marie Metallodynamers: Neutral double-dynamic metallosupramolecular polymers Journal Article In: CHEMISTRY-AN ASIAN JOURNAL, 3 (8-9), pp. 1324–1335, 2008, ISSN: 1861-4728. @article{chow_metallodynamers:_2008, title = {Metallodynamers: Neutral double-dynamic metallosupramolecular polymers}, author = {Chow, Cheuk-Fai and Fujii, Shunsuke and Lehn, Jean-Marie}, doi = {10.1002/asia.200800101}, issn = {1861-4728}, year = {2008}, date = {2008-01-01}, journal = {CHEMISTRY-AN ASIAN JOURNAL}, volume = {3}, number = {8-9}, pages = {1324--1335}, abstract = {Nine neutral dynamic metallosupramolecular polymers (metallodynamers) based on acyl hydrazone derived metal coordination centers (Co2+, Ni2+, Zn2+, and Cd2+) were generated through self-assembly polymerization. These are linear coordination polymers with specific optical and mechanical properties. Monomer selection was found to take place in a mixture of subcomponents (carboxyaldehydes and bisacyl hydrazides) driven by hexacoordination to a specific metal ion. Most importantly, the metallodynamers were found to modify their constitution by exchanging and reshuffling their components with another metallodynamer through ligand exchange at the metal coordination site in solution as well as in the neat phase. As a result, the materials undergo remarkable changes in both their mechanical and optical properties.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Nine neutral dynamic metallosupramolecular polymers (metallodynamers) based on acyl hydrazone derived metal coordination centers (Co2+, Ni2+, Zn2+, and Cd2+) were generated through self-assembly polymerization. These are linear coordination polymers with specific optical and mechanical properties. Monomer selection was found to take place in a mixture of subcomponents (carboxyaldehydes and bisacyl hydrazides) driven by hexacoordination to a specific metal ion. Most importantly, the metallodynamers were found to modify their constitution by exchanging and reshuffling their components with another metallodynamer through ligand exchange at the metal coordination site in solution as well as in the neat phase. As a result, the materials undergo remarkable changes in both their mechanical and optical properties. |
Hickman, David T; Sreenivasachary, Nampally ; Lehn, Jean-Marie Synthesis of components for the generation of constitutional dynamic analogues of nucleic acids Journal Article In: HELVETICA CHIMICA ACTA, 91 (1), pp. 1–20, 2008, ISSN: 0018-019X. @article{hickman_synthesis_2008, title = {Synthesis of components for the generation of constitutional dynamic analogues of nucleic acids}, author = {Hickman, David T. and Sreenivasachary, Nampally and Lehn, Jean-Marie}, doi = {10.1002/hlca.200890022}, issn = {0018-019X}, year = {2008}, date = {2008-01-01}, journal = {HELVETICA CHIMICA ACTA}, volume = {91}, number = {1}, pages = {1--20}, abstract = {The introduction of dynamic covalent polymers, in which the monomer units are linked by reversible covalent bonds and can undergo component exchange, opens up new possibilities for the generation of functional materials. Extending this approach to the generation of dynamic biopolymers in aqueous media, which are able to adapt constitution (sequence, length) to external factors (e.g., environment, medium, template), would provide an alternative approach to the de novo design of functional dynamic bio-macromolecules. As a first step towards this goal, various mono- and bifunctionalised (hetero- and homotopic) nucleic acid-derived building blocks of type I-X have been synthesised for the generation of dynamic main-chain and side-chain reversible nucleic acid analogues. Hydrazide- and/or acetal (protected carbonyl)-functionalised components were selected, which differ in terms of flexibility, length, net formal charge, and hydrazide/acetal substituents, in order to explore how such factors may affect the properties (structure, solubility, molecular recognition features) of the polymer products that may be generated by polycondensation.}, keywords = {}, pubstate = {published}, tppubtype = {article} } The introduction of dynamic covalent polymers, in which the monomer units are linked by reversible covalent bonds and can undergo component exchange, opens up new possibilities for the generation of functional materials. Extending this approach to the generation of dynamic biopolymers in aqueous media, which are able to adapt constitution (sequence, length) to external factors (e.g., environment, medium, template), would provide an alternative approach to the de novo design of functional dynamic bio-macromolecules. As a first step towards this goal, various mono- and bifunctionalised (hetero- and homotopic) nucleic acid-derived building blocks of type I-X have been synthesised for the generation of dynamic main-chain and side-chain reversible nucleic acid analogues. Hydrazide- and/or acetal (protected carbonyl)-functionalised components were selected, which differ in terms of flexibility, length, net formal charge, and hydrazide/acetal substituents, in order to explore how such factors may affect the properties (structure, solubility, molecular recognition features) of the polymer products that may be generated by polycondensation. |
Barluenga, Sofia ; Wang, Cuihua ; Fontaine, Jean-Gonzague ; Aouadi, Kaiss ; Beebe, Kristin ; Tsutsumi, Shinji ; Neckers, Len ; Winssinger, Nicolas Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor Journal Article In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47 (23), pp. 4432–4435, 2008, ISSN: 1433-7851. @article{barluenga_divergent_2008, title = {Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor}, author = {Barluenga, Sofia and Wang, Cuihua and Fontaine, Jean-Gonzague and Aouadi, Kaiss and Beebe, Kristin and Tsutsumi, Shinji and Neckers, Len and Winssinger, Nicolas}, doi = {10.1002/anie.200800233}, issn = {1433-7851}, year = {2008}, date = {2008-01-01}, journal = {ANGEWANDTE CHEMIE-INTERNATIONAL EDITION}, volume = {47}, number = {23}, pages = {4432--4435}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Garcia-Cuadrado, Domingo ; Barluenga, Sofia ; Winssinger, Nicolas Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents Journal Article In: CHEMICAL COMMUNICATIONS, (38), pp. 4619–4621, 2008, ISSN: 1359-7345. @article{garcia-cuadrado_diversity-oriented_2008, title = {Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents}, author = {Garcia-Cuadrado, Domingo and Barluenga, Sofia and Winssinger, Nicolas}, doi = {10.1039/b807869f}, issn = {1359-7345}, year = {2008}, date = {2008-01-01}, journal = {CHEMICAL COMMUNICATIONS}, number = {38}, pages = {4619--4621}, abstract = {A concise sequence utilizing a Petasis three component reaction followed by a tandem aza-Cope-Mannich cyclization afforded novel polycyclic heterocycles in good yield; alternative iminium cyclization based on a Pictet-Spengler reaction or aminal formation led to divergent pathways affording skeletal diversity.}, keywords = {}, pubstate = {published}, tppubtype = {article} } A concise sequence utilizing a Petasis three component reaction followed by a tandem aza-Cope-Mannich cyclization afforded novel polycyclic heterocycles in good yield; alternative iminium cyclization based on a Pictet-Spengler reaction or aminal formation led to divergent pathways affording skeletal diversity. |
Pianowski, Zbigniew L; Winssinger, Nicolas Nucleic acid encoding to program self-assembly in chemical biology Journal Article In: CHEMICAL SOCIETY REVIEWS, 37 (7), pp. 1330–1336, 2008, ISSN: 0306-0012. @article{pianowski_nucleic_2008, title = {Nucleic acid encoding to program self-assembly in chemical biology}, author = {Pianowski, Zbigniew L. and Winssinger, Nicolas}, doi = {10.1039/b706610b}, issn = {0306-0012}, year = {2008}, date = {2008-01-01}, journal = {CHEMICAL SOCIETY REVIEWS}, volume = {37}, number = {7}, pages = {1330--1336}, abstract = {This tutorial review serves as an introduction to the use of oligonucleotides and in particular peptide nucleic acids (PNAs) to encode function beyond heredity. Applications in chemical biology are reviewed starting with the use of nucleic acid tags to program self-assembled microarrays of small and macromolecules, followed by the use of nucleic acid templated reactions for the purpose of DNA or RNA sensing and finally, the use of nucleic acid templates to display ligands.}, keywords = {}, pubstate = {published}, tppubtype = {article} } This tutorial review serves as an introduction to the use of oligonucleotides and in particular peptide nucleic acids (PNAs) to encode function beyond heredity. Applications in chemical biology are reviewed starting with the use of nucleic acid tags to program self-assembled microarrays of small and macromolecules, followed by the use of nucleic acid templated reactions for the purpose of DNA or RNA sensing and finally, the use of nucleic acid templates to display ligands. |
Prikhod'ko, Alexander I; Durola, Fabien ; Sauvage, Jean-Pierre Iron(II)-templated synthesis of [3]rotaxanes by passing two threads through the same ring Journal Article In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130 (2), pp. 448+, 2008, ISSN: 0002-7863. @article{prikhodko_ironii-templated_2008, title = {Iron(II)-templated synthesis of [3]rotaxanes by passing two threads through the same ring}, author = {Prikhod'ko, Alexander I. and Durola, Fabien and Sauvage, Jean-Pierre}, doi = {10.1021/ja078216p}, issn = {0002-7863}, year = {2008}, date = {2008-01-01}, journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY}, volume = {130}, number = {2}, pages = {448+}, abstract = {The three-dimensional template effect of an octahedral iron(II) center has been exploited for threading two coordinating molecular units, each one is a bidentate 3.3'-biisoquinoline ligand bearing p-anisyl groups, through a coordinating 41-membered macrocycle containing the same endocyclic but nonstreically hindering chelate. The double threading process is driven by coordination of three bidentate ligands to the iron(II) center. By replacing the threads decorated with p-anisyl substituents by analogous long-chain ligands bearing appropriate end-functions (azide), the double threading process is as efficient as with the shorter (p-anisyl) chelates. An efficient quadruple end-functionalization reaction based on the copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition (”click” chemistry) affords the desired iron(II)-complexed two-string [3]rotaxane in excellent yield.}, keywords = {}, pubstate = {published}, tppubtype = {article} } The three-dimensional template effect of an octahedral iron(II) center has been exploited for threading two coordinating molecular units, each one is a bidentate 3.3'-biisoquinoline ligand bearing p-anisyl groups, through a coordinating 41-membered macrocycle containing the same endocyclic but nonstreically hindering chelate. The double threading process is driven by coordination of three bidentate ligands to the iron(II) center. By replacing the threads decorated with p-anisyl substituents by analogous long-chain ligands bearing appropriate end-functions (azide), the double threading process is as efficient as with the shorter (p-anisyl) chelates. An efficient quadruple end-functionalization reaction based on the copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition (”click” chemistry) affords the desired iron(II)-complexed two-string [3]rotaxane in excellent yield. |
Beyler, Maryline ; Heitz, Valerie ; Sauvage, Jean-Pierre Quantitative formation of a tetraporphyrin [2] catenane via copper and zinc coordination Journal Article In: CHEMICAL COMMUNICATIONS, (42), pp. 5396–5398, 2008, ISSN: 1359-7345. @article{beyler_quantitative_2008, title = {Quantitative formation of a tetraporphyrin [2] catenane via copper and zinc coordination}, author = {Beyler, Maryline and Heitz, Valerie and Sauvage, Jean-Pierre}, doi = {10.1039/b811013a}, issn = {1359-7345}, year = {2008}, date = {2008-01-01}, journal = {CHEMICAL COMMUNICATIONS}, number = {42}, pages = {5396--5398}, abstract = {A [2] catenane is formed quantitatively by mixing substituted 1,10-phenanthroline- based chelates with copper(I) acting as central template, the ring- forming reaction being based on 1the coordination of pyridinic bidentate ligands onto the zinc atoms of the four porphyrins surrounding the core of the molecule.}, keywords = {}, pubstate = {published}, tppubtype = {article} } A [2] catenane is formed quantitatively by mixing substituted 1,10-phenanthroline- based chelates with copper(I) acting as central template, the ring- forming reaction being based on 1the coordination of pyridinic bidentate ligands onto the zinc atoms of the four porphyrins surrounding the core of the molecule. |
Ventura, Barbara ; Barigelletti, Francesco ; Durola, Fabien ; Flamigni, Lucia ; Sauvage, Jean-Pierre ; Wenger, Oliver S Fe(II), Ru(II) and Re(I) complexes of endotopic, sterically non-hindering, U-shaped 8,8'-disubstituted-3,3'-biisoquinoline ligands: syntheses and spectroscopic properties Journal Article In: DALTON TRANSACTIONS, (4), pp. 491–498, 2008, ISSN: 1477-9226. @article{ventura_feii_2008, title = {Fe(II), Ru(II) and Re(I) complexes of endotopic, sterically non-hindering, U-shaped 8,8'-disubstituted-3,3'-biisoquinoline ligands: syntheses and spectroscopic properties}, author = {Ventura, Barbara and Barigelletti, Francesco and Durola, Fabien and Flamigni, Lucia and Sauvage, Jean-Pierre and Wenger, Oliver S.}, doi = {10.1039/b712834g}, issn = {1477-9226}, year = {2008}, date = {2008-01-01}, journal = {DALTON TRANSACTIONS}, number = {4}, pages = {491--498}, abstract = {The redox behaviour, optical-absorption spectra and emission properties of U-shaped and elongated disubstituted biisoquinoline ligands and of derived octahedral Fe(II), Ru(II), and Re(I) complexes are reported. The ligands are 8,8'-dichloro-3,3'-biisoquinoline (1), 8,8'-dianisyl-3,3'-biisoquinoline (2), and 8,8'-di(phenylanisyl)-3,3'-biisoquinoline (3), and the complexes are [Fe(2)(3)](2+), [Fe(3)(3)](2+), [Ru(1)(phen)(2)](2+), [Ru(2)(3)](2+), [Ru(3)(3)](2+), [Re(2)(py)(CO)(3)](+), and [Re(3)(py)(CO)(3)](+). For the ligands, the optical properties as observed in dichloromethane are in line with expectations based on the predominant (1)pi pi* nature of the involved excited states, with contributions at lower energies from (1)n pi* and (ILCT)-I-1 (intraligand charge transfer) transitions. For all of the Fe(II), Ru(II), and Re(I) complexes, studied in acetonitrile, the transitions associated with the lowest-energy absorption band are of (MLCT)-M-1 (metal-to-ligand charge transfer) nature. The emission properties, as observed at room temperature and at 77 K, can be described as follows: (i) the Fe(II) complexes do not emit, either at room temperature or at 77 K; (ii) the room-temperature emission of the Ru(II) complexes (phi(em) textbackslashtextbackslashtextgreater 10(-3), tau in the mu s range) is of mixed (MLCT)-M-3/(LC)-L-3 character (and similarly at 77 K); and (iii) the room-temperature emission of the Re(I) complexes (phi(em) similar to 3 x 10(-3), tau textbackslashtextbackslashtextless 1 ns) is of (MLCT)-M-3 character and becomes of (LC)-L-3 (ligand-centered) character (tau in the ms time scale) at 77 K. The interplay of the involved excited states in determining the luminescence output is examined.}, keywords = {}, pubstate = {published}, tppubtype = {article} } The redox behaviour, optical-absorption spectra and emission properties of U-shaped and elongated disubstituted biisoquinoline ligands and of derived octahedral Fe(II), Ru(II), and Re(I) complexes are reported. The ligands are 8,8'-dichloro-3,3'-biisoquinoline (1), 8,8'-dianisyl-3,3'-biisoquinoline (2), and 8,8'-di(phenylanisyl)-3,3'-biisoquinoline (3), and the complexes are [Fe(2)(3)](2+), [Fe(3)(3)](2+), [Ru(1)(phen)(2)](2+), [Ru(2)(3)](2+), [Ru(3)(3)](2+), [Re(2)(py)(CO)(3)](+), and [Re(3)(py)(CO)(3)](+). For the ligands, the optical properties as observed in dichloromethane are in line with expectations based on the predominant (1)pi pi* nature of the involved excited states, with contributions at lower energies from (1)n pi* and (ILCT)-I-1 (intraligand charge transfer) transitions. For all of the Fe(II), Ru(II), and Re(I) complexes, studied in acetonitrile, the transitions associated with the lowest-energy absorption band are of (MLCT)-M-1 (metal-to-ligand charge transfer) nature. The emission properties, as observed at room temperature and at 77 K, can be described as follows: (i) the Fe(II) complexes do not emit, either at room temperature or at 77 K; (ii) the room-temperature emission of the Ru(II) complexes (phi(em) textbackslashtextbackslashtextgreater 10(-3), tau in the mu s range) is of mixed (MLCT)-M-3/(LC)-L-3 character (and similarly at 77 K); and (iii) the room-temperature emission of the Re(I) complexes (phi(em) similar to 3 x 10(-3), tau textbackslashtextbackslashtextless 1 ns) is of (MLCT)-M-3 character and becomes of (LC)-L-3 (ligand-centered) character (tau in the ms time scale) at 77 K. The interplay of the involved excited states in determining the luminescence output is examined. |
Sauvage, Jean-Pierre ; Collin, Jean-Paul ; Faiz, Jonathan A; Frey, Julien ; Heitz, Valerie ; Tock, Christian Porphyrin-based catenanes and rotaxanes Journal Article In: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 12 (8), pp. 881–905, 2008, ISSN: 1088-4246. @article{sauvage_porphyrin-based_2008, title = {Porphyrin-based catenanes and rotaxanes}, author = {Sauvage, Jean-Pierre and Collin, Jean-Paul and Faiz, Jonathan A. and Frey, Julien and Heitz, Valerie and Tock, Christian}, doi = {10.1142/S1088424608000285}, issn = {1088-4246}, year = {2008}, date = {2008-01-01}, journal = {JOURNAL OF PORPHYRINS AND PHTHALOCYANINES}, volume = {12}, number = {8}, pages = {881--905}, abstract = {Catenanes and rotaxanes containing porphyrin subunits have become popular synthetic targets because of the large variety of available synthetic strategies including the coordination chemistry of metalated porphyrins, coupled with the many attractive physical properties of porphyrins. The present review article outlines various synthetic approaches and templating strategies that have been used to prepare a range of mechanically interlocked architectures that incorporate porphyrins as fundamental subunits either grafted onto macrocycles or as stoppers. These species are of interest in relation to recreating natural processes such as the photosynthetic apparatus or enzyme binding sites. In recent years, “Molecular machines” have also experienced a spectacular development. Porphyrin-based rotaxanes are particularly promising in relation to this research field, this is shown by the elaboration of a “molecular press” whose properties will be briefly discussed in this review. Copyright (c) 2008 Society of Porphyrins & Phthalocyanines.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Catenanes and rotaxanes containing porphyrin subunits have become popular synthetic targets because of the large variety of available synthetic strategies including the coordination chemistry of metalated porphyrins, coupled with the many attractive physical properties of porphyrins. The present review article outlines various synthetic approaches and templating strategies that have been used to prepare a range of mechanically interlocked architectures that incorporate porphyrins as fundamental subunits either grafted onto macrocycles or as stoppers. These species are of interest in relation to recreating natural processes such as the photosynthetic apparatus or enzyme binding sites. In recent years, “Molecular machines” have also experienced a spectacular development. Porphyrin-based rotaxanes are particularly promising in relation to this research field, this is shown by the elaboration of a “molecular press” whose properties will be briefly discussed in this review. Copyright (c) 2008 Society of Porphyrins & Phthalocyanines. |
Champin, Benoit ; Sartor, Valerie ; Sauvage, Jean-Pierre A highly rigid ditopic conjugate with orthogonal coordination axes and its zinc(II) and copper(II) complexes Journal Article In: NEW JOURNAL OF CHEMISTRY, 32 (6), pp. 1048–1054, 2008, ISSN: 1144-0546. @article{champin_highly_2008, title = {A highly rigid ditopic conjugate with orthogonal coordination axes and its zinc(II) and copper(II) complexes}, author = {Champin, Benoit and Sartor, Valerie and Sauvage, Jean-Pierre}, doi = {10.1039/b713367g}, issn = {1144-0546}, year = {2008}, date = {2008-01-01}, journal = {NEW JOURNAL OF CHEMISTRY}, volume = {32}, number = {6}, pages = {1048--1054}, abstract = {A highly rigid ditopic ligand has been prepared which consists of a terpy fragment connected in the back to a phen nucleus via a 1,4-phenylene linker. The chemical structure of the presently reported ligand is such that the coordination axes of the two chelates are orthogonal to one another. The reaction of this phen-terpy conjugate with zinc(II) surprisingly affords in good yield a dinuclear complex in spite of the tension of the generated structure, whereas coordination of copper(II) centres to the two-chelate ligand enables the formation of the trinuclear complex also.}, keywords = {}, pubstate = {published}, tppubtype = {article} } A highly rigid ditopic ligand has been prepared which consists of a terpy fragment connected in the back to a phen nucleus via a 1,4-phenylene linker. The chemical structure of the presently reported ligand is such that the coordination axes of the two chelates are orthogonal to one another. The reaction of this phen-terpy conjugate with zinc(II) surprisingly affords in good yield a dinuclear complex in spite of the tension of the generated structure, whereas coordination of copper(II) centres to the two-chelate ligand enables the formation of the trinuclear complex also. |
1975 |
Hartman, F C; LaMuraglia, G M; Tomozawa, Y; Wolfenden, R The influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group Journal Article In: Biochemistry, 14 (24), pp. 5274–5279, 1975, ISSN: 0006-2960. @article{hartman_influence_1975, title = {The influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group}, author = {Hartman, F. C. and LaMuraglia, G. M. and Tomozawa, Y. and Wolfenden, R.}, issn = {0006-2960}, year = {1975}, date = {1975-12-01}, journal = {Biochemistry}, volume = {14}, number = {24}, pages = {5274--5279}, abstract = {Ionization effects on the binding of the potential transition state analogues 2-phosphoglycolate and 2-phosphoglycolohydroxamate appear to be attributable to the changing state of ionization of the ligands themselves, therefore it is unnecessary to postulate the additional involvement of an ionizing residue at the active site of triosephosphate isomerase to explain the influence of changing pH on Ki in the neutral range. The binding of the competitive inhibitor inorganic sulfate is insensitive to changing pH in the neutral range. 3-Chloroacetol sulfate, synthesized as an active-site-specific reagent for triosephosphate isomerase, is used to provide an indication of the pKa of the essential carboxyl group of this enzyme. Previously described active-site-specific reagents for the isomerase were phosphate esters, and their changing state of ionization (accompanied by possible changes in their affinity for the active site) may have complicated earlier attempts to determine the pKa of the essential carboxyl group from the pH dependence of the rate of inactivation. Being a strong monoprotic acid, chloroacetol sulfate is better suited to the determination of the pKa of the carboxyl group. Chloroacetol sulfate inactivates triosephosphate isomerase by the selective esterification of the same carboxyl group as that which is esterified by the phosphate esters described earlier. From the pH dependence of the rate of inactivation of yeast triosephosphate isomerase, the apparent pKa of the active-site carboxyl group is estimated as 3.9 +/- 0.1.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Ionization effects on the binding of the potential transition state analogues 2-phosphoglycolate and 2-phosphoglycolohydroxamate appear to be attributable to the changing state of ionization of the ligands themselves, therefore it is unnecessary to postulate the additional involvement of an ionizing residue at the active site of triosephosphate isomerase to explain the influence of changing pH on Ki in the neutral range. The binding of the competitive inhibitor inorganic sulfate is insensitive to changing pH in the neutral range. 3-Chloroacetol sulfate, synthesized as an active-site-specific reagent for triosephosphate isomerase, is used to provide an indication of the pKa of the essential carboxyl group of this enzyme. Previously described active-site-specific reagents for the isomerase were phosphate esters, and their changing state of ionization (accompanied by possible changes in their affinity for the active site) may have complicated earlier attempts to determine the pKa of the essential carboxyl group from the pH dependence of the rate of inactivation. Being a strong monoprotic acid, chloroacetol sulfate is better suited to the determination of the pKa of the carboxyl group. Chloroacetol sulfate inactivates triosephosphate isomerase by the selective esterification of the same carboxyl group as that which is esterified by the phosphate esters described earlier. From the pH dependence of the rate of inactivation of yeast triosephosphate isomerase, the apparent pKa of the active-site carboxyl group is estimated as 3.9 +/- 0.1. |
Caras, I; Shapiro, B Partial purification and properties of microsomal phosphatidate phosphohydrolase from rat liver Journal Article In: Biochimica Et Biophysica Acta, 409 (2), pp. 201–211, 1975, ISSN: 0006-3002. @article{caras_partial_1975, title = {Partial purification and properties of microsomal phosphatidate phosphohydrolase from rat liver}, author = {Caras, I. and Shapiro, B.}, issn = {0006-3002}, year = {1975}, date = {1975-11-01}, journal = {Biochimica Et Biophysica Acta}, volume = {409}, number = {2}, pages = {201--211}, abstract = {Microsomal phosphatidate phosphohydrolase (phosphatidate phosphatase EC 3.1.3.4) was solubilized and fractionated to yield at least two distinct enzymatically active fractions. One, denoted FA, was non-specific, had a relatively high Km for phosphatidic acid and was insensitive to inhibition by diacylglycerol. The second fraction, FB, was specific for phosphatidates, had a low Km, and was inhibited, non-competitively, by diacylglycerol. FA exhibited a sigmoid substrate-activity curve. The isolated FB aggregated to particles of about 10(6) in the absence of salts and could be dissociated by the addition of monovalent cations at ionic strength 0.4-0.6 to about 2-10(5) daltons and thereby doubled its activity. Dissociation was time- and temperature-dependent. F- was inhibitory. Divalent ions were not required for the activity of FA or FB and inhibited at concentrations exceeding 1 mM.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Microsomal phosphatidate phosphohydrolase (phosphatidate phosphatase EC 3.1.3.4) was solubilized and fractionated to yield at least two distinct enzymatically active fractions. One, denoted FA, was non-specific, had a relatively high Km for phosphatidic acid and was insensitive to inhibition by diacylglycerol. The second fraction, FB, was specific for phosphatidates, had a low Km, and was inhibited, non-competitively, by diacylglycerol. FA exhibited a sigmoid substrate-activity curve. The isolated FB aggregated to particles of about 10(6) in the absence of salts and could be dissociated by the addition of monovalent cations at ionic strength 0.4-0.6 to about 2-10(5) daltons and thereby doubled its activity. Dissociation was time- and temperature-dependent. F- was inhibitory. Divalent ions were not required for the activity of FA or FB and inhibited at concentrations exceeding 1 mM. |
Giangrande, M; Kim, Y W; Mizukami, H N-terminal spin label studies of hemoglobin, Ligand and pH dependence Journal Article In: Biochimica Et Biophysica Acta, 412 (1), pp. 187–193, 1975, ISSN: 0006-3002. @article{giangrande_n-terminal_1975, title = {N-terminal spin label studies of hemoglobin, Ligand and pH dependence}, author = {Giangrande, M. and Kim, Y. W. and Mizukami, H.}, issn = {0006-3002}, year = {1975}, date = {1975-11-01}, journal = {Biochimica Et Biophysica Acta}, volume = {412}, number = {1}, pages = {187--193}, abstract = {Human hemoglobin was spin labeled with 4-isothiocanato-2,2,6,6-tetramethyl-piperdinooxyl, which is known to bind specifically to the N-terminal alpha-amino groups of proteins and slightly to the reactive sulfhydryl groups. Electron spin resonance (ESR) analysis indicated a partially resolved five-line spectrum, suggesting that the label was attached to at least two different binding sites. Using specific blocking reagents prior to spin labeling, the two binding sites were attributed to the sulfhydryl group of beta-93 (immobile) and the alpha-amino group of the N-terminal valines (mobile). The relative motion of the spin at one set of binding sites was restricted regardless of the state of ligation and pH, while the motion at the other site showed dependence on those parameters, e.g. the spin-labeled N-terminal ends of deoxyhemoglobin have restricted motion at all pH ranges studied, while those of oxyhemoglobin are relatively free to move at the basic pH range, but become more restricted in the acidic pH range.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Human hemoglobin was spin labeled with 4-isothiocanato-2,2,6,6-tetramethyl-piperdinooxyl, which is known to bind specifically to the N-terminal alpha-amino groups of proteins and slightly to the reactive sulfhydryl groups. Electron spin resonance (ESR) analysis indicated a partially resolved five-line spectrum, suggesting that the label was attached to at least two different binding sites. Using specific blocking reagents prior to spin labeling, the two binding sites were attributed to the sulfhydryl group of beta-93 (immobile) and the alpha-amino group of the N-terminal valines (mobile). The relative motion of the spin at one set of binding sites was restricted regardless of the state of ligation and pH, while the motion at the other site showed dependence on those parameters, e.g. the spin-labeled N-terminal ends of deoxyhemoglobin have restricted motion at all pH ranges studied, while those of oxyhemoglobin are relatively free to move at the basic pH range, but become more restricted in the acidic pH range. |
0000 |
0000. @book{noauthor_laboratoire_nodate, title = {Laboratoire des Systèmes Complexes hors équilibre (Thomas HERMANS) textbackslashtextbackslashtextbar Institut de Science et d'Ingénierie Supramoléculaires}, url = {http://isis.unistra.fr/laboratoire-des-systemes-complexes-hors-equilibre-thomas-hermans/}, urldate = {2018-10-08}, keywords = {}, pubstate = {published}, tppubtype = {book} } |
, Molecule–Graphene Hybrid Materials with Tunable Mechanoresponse: Highly Sensitive Pressure Sensors for Health Monitoring Journal Article In: 0000. @article{, title = {Molecule–Graphene Hybrid Materials with Tunable Mechanoresponse: Highly Sensitive Pressure Sensors for Health Monitoring}, author = { }, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Journal Article In: 0000. @article{, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Publications
2008 |
Pre-programmed bicomponent porous networks at the solid-liquid interface: the low concentration regime Journal Article In: CHEMICAL COMMUNICATIONS, (42), pp. 5289–5291, 2008, ISSN: 1359-7345. |
Self-assembly of hydrogen-bond assisted supramolecular azatriphenylene architectures Journal Article In: SOFT MATTER, 4 (2), pp. 303–310, 2008, ISSN: 1744-683X. |
Self-assembly of discotic molecules into mesoscopic crystals by solvent-vapour annealing Journal Article In: SOFT MATTER, 4 (10), pp. 2064–2070, 2008, ISSN: 1744-683X. |
Exploring electronic transport in molecular junctions by conducting atomic force microscopy Incollection In: {Samori, P} (Ed.): STM AND AFM STUDIES ON (BIO)MOLECULAR SYSTEMS: UNRAVELLING THE NANOWORLD, 285 , pp. 157–202, 2008, ISBN: 978-3-540-78394-7. |
DOSY NMR experiments as a tool for the analysis of constitutional and motional dynamic processes: Implementation for the driven evolution of dynamic combinatorial libraries of helical strands Journal Article In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47 (12), pp. 2235–2239, 2008, ISSN: 1433-7851. |
Glycodynamers: Fluorescent dynamic analogues of polysaccharides Journal Article In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47 (19), pp. 3556–3559, 2008, ISSN: 1433-7851. |
A Jubilee 60th Congress of the Association of Czech and Slovak chemical company. Olomouc, 1st-4th September 2008 - Abstracts Journal Article In: CHEMICKE LISTY, 102 (8), pp. 595–759, 2008, ISSN: 0009-2770. |
Structural selection in G-quartet-based hydrogels and controlled release of bioactive molecules Journal Article In: CHEMISTRY-AN ASIAN JOURNAL, 3 (1), pp. 134–139, 2008, ISSN: 1861-4728. |
Metallodynamers: Neutral double-dynamic metallosupramolecular polymers Journal Article In: CHEMISTRY-AN ASIAN JOURNAL, 3 (8-9), pp. 1324–1335, 2008, ISSN: 1861-4728. |
Synthesis of components for the generation of constitutional dynamic analogues of nucleic acids Journal Article In: HELVETICA CHIMICA ACTA, 91 (1), pp. 1–20, 2008, ISSN: 0018-019X. |
Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor Journal Article In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47 (23), pp. 4432–4435, 2008, ISSN: 1433-7851. |
Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents Journal Article In: CHEMICAL COMMUNICATIONS, (38), pp. 4619–4621, 2008, ISSN: 1359-7345. |
Nucleic acid encoding to program self-assembly in chemical biology Journal Article In: CHEMICAL SOCIETY REVIEWS, 37 (7), pp. 1330–1336, 2008, ISSN: 0306-0012. |
Iron(II)-templated synthesis of [3]rotaxanes by passing two threads through the same ring Journal Article In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130 (2), pp. 448+, 2008, ISSN: 0002-7863. |
Quantitative formation of a tetraporphyrin [2] catenane via copper and zinc coordination Journal Article In: CHEMICAL COMMUNICATIONS, (42), pp. 5396–5398, 2008, ISSN: 1359-7345. |
Fe(II), Ru(II) and Re(I) complexes of endotopic, sterically non-hindering, U-shaped 8,8'-disubstituted-3,3'-biisoquinoline ligands: syntheses and spectroscopic properties Journal Article In: DALTON TRANSACTIONS, (4), pp. 491–498, 2008, ISSN: 1477-9226. |
Porphyrin-based catenanes and rotaxanes Journal Article In: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 12 (8), pp. 881–905, 2008, ISSN: 1088-4246. |
A highly rigid ditopic conjugate with orthogonal coordination axes and its zinc(II) and copper(II) complexes Journal Article In: NEW JOURNAL OF CHEMISTRY, 32 (6), pp. 1048–1054, 2008, ISSN: 1144-0546. |
1975 |
The influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group Journal Article In: Biochemistry, 14 (24), pp. 5274–5279, 1975, ISSN: 0006-2960. |
Partial purification and properties of microsomal phosphatidate phosphohydrolase from rat liver Journal Article In: Biochimica Et Biophysica Acta, 409 (2), pp. 201–211, 1975, ISSN: 0006-3002. |
N-terminal spin label studies of hemoglobin, Ligand and pH dependence Journal Article In: Biochimica Et Biophysica Acta, 412 (1), pp. 187–193, 1975, ISSN: 0006-3002. |
0000 |
0000. |
Molecule–Graphene Hybrid Materials with Tunable Mechanoresponse: Highly Sensitive Pressure Sensors for Health Monitoring Journal Article In: 0000. |
Journal Article In: 0000. |