September 2022
Prof. Martin Oestreich “Transfer of reactive intermediates from one molecule to another”
Prof. Martin Oestreich TU Berlin, Berlin, Germany
Find out more »Dr. Adrien Quintard “From greener synthetic methodologies to new materials”
Dr. Adrien Quintard Université Grenoble-Alpes, Gières
Find out more »October 2022
Prof. Huw Davies “Collaborative Approach for Catalyst-Controlled Site-Selective and Enantioselective C-H Functionalization”
Huw M. L. Davies Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322 E-Mail : hmdavie@emory.edu One of the signature challenges of the NSF Center for Chemical Innovation on Selective C-H Functionalization (CCHF) has been the design of catalysts to control site selective C-H functionalization reactions. Dirhodium tetracarboxylates have been very effective in this regard because the carboxylate ligands self-assemble on coordination to the dirhodium to generate high symmetry chiral catalysts of defined shape and size. This presentation…
Find out more »Prof. Dennis Gillingham “Chemical modifications of DNA and how they inspired a new method for target protein degradation”
Prof. Dennis Gillingham University of Basel “Chemical modifications of DNA and how they inspired a new method for target protein degradation” Brief Abstract: Guanine is one of the most reactive bases in DNA and is often the site of action of DNA-modifying drugs. Alkylation damage at oxygen in position six of guanine is directly repaired by an unusual suicide protein known as methylguanine methyltransferase (MGMT). The protein performs an SN2 reaction at the alkylation damage, thus directly accepting the alkyl…
Find out more »Prof. Rafal Klajn “Electrostatic self-assembly of nanoparticles into static and out-of-equilibrium materials”
Prof. Rafal Klajn Weizmann Institute of Science Self-assembly of inorganic nanoparticles (NPs) into ordered structures (“superlattices”) has led to a wide range of nanomaterials with unique optical, electronic, and catalytic properties. Various interactions have been employed to direct the crystallization of NPs, including van der Waals forces, hydrogen bonding, as well as electric and magnetic dipolar interactions. Among them, Coulombic interactions have remained largely unexplored, owing to the rapid charge ligand exchange between NPs bearing high densities of opposite charges.…
Find out more »November 2022
Prof. Nathalie Katsonis “Chemical origin of protocells and motility in primeval oceans”
Prof. Nathalie Katsonis University of Groningen Our research aims at uncovering some of the molecular mechanisms at the origin of functional movement, in systems of interacting molecules. Movement is a defining feature of life. It enables bacteria to overcome diffusion when seeking nutrients and is essential in eukaryotes to achieve embryogenesis. This functional movement is born at the level of molecular interactions, yet we still do not know how motile molecular systems emerged in the early Earth’s oceans. It is…
Find out more »December 2022
Alexandre Detappe “Nanomedicine development – The case of Multiple Myeloma”
Alexandre Detappe ICANS - Institut de cancérologie Strasbourg Europe Abstract In the past decades, considerable progress has been made in our understanding and treatment of multiple myeloma. Several challenges remain including our abilities to longitudinally image tumor responses to treatment, to combine various therapeutic agents with different mechanisms of action but with overlapping toxicities, and to efficiently harness the power of the immune system to augment remission and/or to induce permanent cures. Nanomedicine may help to address many of…
Find out more »Prof. Jeremy Wulff “Universal Crosslinkers for On-Demand Upgrading of Polymer Properties: Synthesis, Structure-Function Relationships, and Applications in Materials Science”
Prof. Jeremy Wulff Université de Victoria, Canada http://web.uvic.ca/%7Ewulff/
Find out more »January 2023
Dr. Pascal Mayer “Pluri-disciplinarity at work: From Next Generation DNA Sequencing to Next Generation Therapeutics”
Dr. Pascal Mayer Alphanosos
Find out more »Prof. Sara Bals “3D Characterization of Nanomaterials under Relevant Conditions by Electron Tomography”
Prof. Sara Bals Electron Microscopy for Materials Science (EMAT) and NANOlab Center of Exellence, University of Antwerp, Antwerp 2020, Belgium Abstract Electron tomography enables one to measure the morphology and composition of nanostructures in three dimensions (3D), even at atomic resolution. However, an emerging challenge is to fully understand the connection between the 3D structure and properties under realistic conditions, including high temperatures as well as in the presence of liquids and gases. Our recent experiments demonstrate the progress…
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