Prof. Simone Fabiano

Linköping University, Sweden

Abstract

Biointegrated neuromorphic hardware holds promise for new protocols to record and regulate signaling in biological systems. Traditional neuromorphic systems relying on silicon face limitations in bio-integration due to circuit complexity, poor biocompatibility, and low energy efficiency. Organic mixed ionic-electronic conductors (OMIECs), owing to their structural resemblance to biomolecules and coupled ionic-electronic transport functionalities, offer an excellent solution for bridging electronics and biology, facilitating energy-efficient signal transduction. In this presentation, I will explore the use of OMIECs to develop organic electrochemical neurons and synapses with ion-mediated spiking. I will discuss their seamless integration with biological nerves and showcase neurosynaptic circuits capable of modulating spiking through neurotransmitters, amino acids, and ions. These soft, flexible organic electrochemical neurons and synapses operate at low energy levels and respond to multiple stimuli, marking a new era for organic bioelectronics.