Dear All,

It is my great pleasure to invite you to the Virtual ISIS Conference that will take place on Monday, May 10th,  at 16.30. We will have a lecture on “Late-Stage Functionalizations” by Prof. Tobias Ritter (Max Planck Institut für Kohlenforschung, Mülheim, Germany, RWTH Aachen University, Aachen, Germany & Massachusetts General Hospital, Boston, USA)

Abstract: Late-stage functionalization reactions should reliably functionalize already complex molecules to quickly access value-added molecular diversity. Late-stage functionalization is desirable in many areas of discovery such as in drug or agrochemical development and a requirement in other areas such as the synthesis of positron-emission tomography (PET) tracers. I will describe the development of novel, modern highly selective reactions in late-stage functionalization, as well as their application in transition-metal-catalyzed and photoredox reactions, with a focus on the synthesis of 18F and 19F containing complex small molecules. In particular, I will describe the development of a broadly useful new C-H functionalization reaction to create molecular complexity for applications in catalysis, drug discovery, and medicine.